KISSPEPTIN - 10

All Details

KISSPEPTIN - 10

KISSPEPTIN - 10 1 VIAL X 10MG VIAL.

Kisspeptin is a hypothalamic peptide that stimulates the release of gonadotropin-releasing hormone (GnRH), triggering the production of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Bodybuilders sometimes use it as an off-label tool to naturally boost testosterone and support post-cycle therapy (PCT) after anabolic steroid use, though it lacks regulatory approval for this purpose.

How Kisspeptin Works in the Body

Kisspeptin acts on the Kiss1 receptor (KISS1R) in the hypothalamus. By turning on the hypothalamic-pituitary-gonadal (HPG) axis, it upregulates the body's natural production of reproductive hormones

Potential Benefits for Bodybuilders

Testosterone Support: By signaling for increased LH output, it can elevate endogenous testosterone levels, which are critical for muscle hypertrophy, strength, and recovery.

Post-Cycle Therapy (PCT): Some athletes use it during PCT to help "kickstart" the body’s natural testosterone production after a cycle of anabolic steroids, which can suppress the HPG axis.

Metabolic Function: Early-stage animal models suggest that kisspeptin signaling may influence fat loss, energy expenditure, and metabolism, though these non-reproductive effects are still being researched.

Libido and Well-being: Clinical studies indicate that kisspeptin can enhance sexual desire and mood, which can be negatively impacted by intensive training or severe hormonal shifts.

Side Effects and Unknowns: Because it works via the HPG axis, using it improperly may disrupt the delicate balance of hormones. Long-term safety data in healthy adult athletes is severely limited.

KISS-10 Dosage

Minimal effective dose: As low as 300 mcg/kg (0.3 mcg/kg) produces robust LH and FSH elevation in healthy men 1,2

Optimal single bolus dose: 1000 mcg/kg (1.0 mcg/kg) achieves maximal gonadotropin stimulation, increasing mean LH from baseline 4.1 IU/L to 12.4 IU/L at 30 minutes 2.